What Are Hormones? Hormones are the body's chemical messengers that travel in the bloodstream to tissues and organs. Hormones affect many physiological activities including growth, metabolism, appetite, puberty and fertility. What are Hormonal Imbalances? Hormonal imbalances are changes in estrogen, progesterone and other hormones that affects women and men. What are the Symptoms of Hormonal Imbalance? Weight Gain Fatigue Anxiety Insomnia Skin & Hair Changes Fertility Heavy &